Thank you all for visiting our booth at the American Thoracic Society International Conference 2015 in Denver last month. It was great to see you and learn more about your specific research interests. Three trends became evident from our conversations and a review of the abstracts presented:
- The pace of exhaled biomarker research is accelerating
- Measurement of Volatile Organic Compounds in exhaled breath is becoming central to the field
- Potentially prognostic genetic markers of lung cancer in breath condensate are emerging
The 21 abstracts below were selected from the full list of ATS 2015 abstracts found at:
http://www.atsjournals.org/doi/book/10.1164/ajrccm-conference.2015
Hopefully we didn’t miss any relevant to the field of exhaled biomarker research, but if we did, please let us know and we’ll update this post.
As a side note, we specifically excluded eNO abstracts since this is becoming established clinically and is essentially a category in of itself. Our focus continues to be on other emerging research.
Happy reading!
| Functional and Inflammatory Abnormalities in Artificial Stone Exposed Workers
Noa Ophir, Yifat Alcalay, Amir Bar-Shai, Lilach Israeli-shany, Rafi Korenstein,Mordechai Kramer, , Elizabeth M. Fireman A46. OCCUPATION, OBESITY, AND LUNG HEALTH, 2015: A1749, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A1749 |
| Exhaled Carbon Monoxide: A Marker of Recent Household Air Pollution Exposure
Alison Lee, , Tiffany Sanchez, Hasan Shahriar, Mahbubul Eunus, Matthew Perzanowski,Joseph Graziano B46. HEALTH EFFECTS OF AIR POLLUTION AND NANOPARTICLES, 2015: A3234, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A3234 |
| Relationship Between Airway Hyperresponsiveness to Hypoosmolar Stimulus and Inflammation in Asthma
Juliy M. Perelman, Anna G. Prikhodko, Evgenia Y. Afanaseva, Evgeniy A. Borodin, ,Viktor P. Kolosov A33. IMMUNE REGULATION OF INFLAMMATION AND AIRWAY HYPERRESPONSIVENESS, 2015: A1348, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A1348 |
| Airway Metabolomics in Asthma
Deepa Rastogi, , Hardik B. Shah, Lizette DeLaRosa, Irwin J. Kurland, Simon D. Spivack C38. BIOMARKERS OF ACUTE AND CHRONIC INFLAMMATION, 2015: A4307, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A4307 |
| Airway Acidity in Critically Ill, Mechanically Ventilated Patients
Michael D. Davis, , Alison J. Montpetit, William Anderson, R K. Elswick, Michelle Jump,Megan A. Scott, John F. Hunt C38. BIOMARKERS OF ACUTE AND CHRONIC INFLAMMATION, 2015: A4339, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A4339 |
| Exhaled microRNAs as Biomarkers of Lung Cancer Case Status
Simon D. Spivack, Miao K. Shi, Juan Lin, Weiguo Han, B61. MANAGING LUNG CANCER SCREENING AND ITS DOWNSTREAM FINDINGS, 2015: A3583, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A3583 |
| Ultrafine Particles (UFP) Content in Exhaled Breath Condensate (EBC) in Asthmatic Children Airways
Elizabeth M. Fireman, Shira Benor, Keren Armoni Dumani, Yfat Alcaly, Guy Gut, Ruth Soferman, Shmuel Kivity, D107. NOVEL ASTHMA EPIDEMIOLOGY AND MECHANISMS, 2015: A6269, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A6269 |
| Detection of microRNAs Associated with Tumor Dissemination and Drug Resistance in Exhaled Breath in Lung Cancer
Wei Le, , W Wong, Mueen Ghani, Rahul Ahuja, Daya Upadhyay B57. GENE REGULATION: MIRNAS AND EPIGENETICS, 2015: A3482, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A3482 |
| Short Term Biological Effects of e-Cigarette Vapor Exposures
Kelly Schweitzer, , Sarah Law, Christophe Poirier, Xianyin Lai, Mu Wang, William D. Kranz, Clinton J. Carroll, Bruce D. Ray, John Goodpaster, Irina Petrache B28. BARRIER DYNAMICS IN THE PULMONARY CIRCULATION, 2015: A2654, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A2654 |
| Comparison of Airway and Systemic Malondialdehyde Levels for Assessment of Oxidative Stress in Cystic Fibrosis
Balazs Antus, Orsolya Drozdovszky, Krisztina Kelemen, Imre Barta, D45. CYSTIC FIBROSIS: FROM ION TRANSPORT TO OXIDANT METABOLISM, 2015: A6005, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A6005 |
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| Exhaled Breath Volatile Organic Compounds can Classify Asthma Patients with High and Low Sputum Eosinophils
Paul Brinkman, Yuanyue Wang, Simone Hashimoto, Hans Weda, Hugo H. Knobel,Teunis J. Vink, Nicholas J. Rattray, Paolo Montuschi, Marco Santonico, Giorgo Pennazza, Arnaldo D’Amico, Peter J. Sterk, Stephen J. Fowler, C38. BIOMARKERS OF ACUTE AND CHRONIC INFLAMMATION, 2015: A4310, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A4310 |
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| Comparison of Breath Volatile Organic Compounds Collected from Healthy Controls, Healthy Smokers, Smokers with COPD, and Ex-Smokers with COPD at Two German Centers for Lung Research (DZL)
Arne Gaida, Olaf Holz, Sven Schuchardt, , Christoph Nell, Ursula Boas, Jens Langejürgen, Stefan Zimmermann, Andreas R. Koczulla, Jens M. Hohlfeld B31. INFLAMMATION AND COPD, 2015: A2727, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A2727 |
| Asthmatic Children that Are Uncontrolled Despite Inhaled Corticosteroids Have a Distinct Breathprint (The PACMAN2 Study)
Susanne Vijverberg, Paul Brinkman, Jan Raaijmakers, Kors Van Der Ent, Peter J. Sterk, , Anke-Hilse Maitland-van Der Zee, Leo Koenderman B21. TRANSLATIONAL ASTHMA RESEARCH, 2015: A2482, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A2482 |
| Detection of Volatile Organic Compounds in the Exhaled Breath as Biomarkers for the Paratuberculosis in Goats by Ion Mobility Spectrometry
Gunther Becher, Heike Koehler, Werner Schueler, Roman Purkhart, , Werner Steinhaeusser, Petra Reinhold A32. MICROBIAL INTERACTIONS AND HOST DEFENSE, 2015: A1340, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A1340 |
| Analysis of Hydrogen Sulfide in Breath
Jack Dummer, , Malina Storer, Maureen P. Swanney, Christopher Frampton, Michael Epton C38. BIOMARKERS OF ACUTE AND CHRONIC INFLAMMATION, 2015: A4336, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A4336 |
| Volumetric Capnography as a Candidate Exhaled Biomarker for Patients with Rib Fractures
Alison Montpetit, , Michael Davis, Megan Scott, Michelle Jump, Leroy Thacker, Emily Cochran, Christi Adams, Lois Rowland, Beth Boering, James Whelan, V. R. Feeser C38. BIOMARKERS OF ACUTE AND CHRONIC INFLAMMATION, 2015: A4338, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A4338 |
| A Comparision on Non-Invasive Biomarkers of Airway Type-2 Inflammation in Asthma
Michael C. Peters, , Nirav R. Bhakta, Prescott G. Woodruff, John V. Fahy B21. TRANSLATIONAL ASTHMA RESEARCH, 2015: A2483, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A2483 |
| Exhaled microRNAs as Biomarkers of Lung Cancer Case Status
Simon D. Spivack, Miao K. Shi, Juan Lin, Weiguo Han, B61. MANAGING LUNG CANCER SCREENING AND ITS DOWNSTREAM FINDINGS, 2015: A3583, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A3583 |
| Exhaled Breath Analysis for Volatile Organic Compounds Reveals New Insights into the Pathogenesis of Irritable Bowel Syndrome
David Grove, Ammar Matloob, Sophia Ali Patel, Vera Okwu, Raed A. Dweik, Naim Alkhouri, A33. IMMUNE REGULATION OF INFLAMMATION AND AIRWAY HYPERRESPONSIVENESS, 2015: A1371, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A1371 |
| Integration of Electronic Nose Technology with Spirometry: Validation of a New Approach for Clinical Breath Analysis
Rianne De Vries, Paul Brinkman, Niki Fens, Erica Dijkers, Simon Bootsma, Frans H.C. De Jongh, P.J. Sterk, C32. CLINICAL ASTHMA II, 2015: A4184, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A4184 |
| Volatile Organic Compounds (VOCs) in Exhaled Breath of Asthma Patients Differ Between Loss of Control and Stable Phase
Niki Fens, , Marianne A. Van De Pol, Paul Brinkman, Maria G. Gerritsen, Lieuwe D.J. Bos, Tamara Dekker, Barbara S. Smids, Christof J. Majoor, Marlous M.S. Sneeboer,René Lutter, Peter J. Sterk C32. CLINICAL ASTHMA II, 2015: A4172, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A4172 |