Research

Stay at the forefront of respiratory science with in-depth explorations of breath biomarker studies, innovative methods, and novel discoveries. From academic breakthroughs to industry-led investigations, find the knowledge shaping future diagnostic and therapeutic strategies.

Monitor airway biomarkers from baseline to peak exposure to washout with serial collections of Exhaled Breath Condensate

Did the Drug Fail, or Did the Measurement Fail?

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Exhaled breath condensate (EBC) is a non-invasive tool that provides airway-level biological context in early-phase respiratory drug development, helping to distinguish whether ambiguous trial results are due to drug failure or inadequate measurement. EBC is most valuable when the pharmacodynamic question is lung-compartment specific and cannot be answered by blood or FeNO, but its biomarkers are exploratory and require a pre-specified analysis plan for meaningful interpretation. While EBC does not provide validated endpoints, its inclusion can inform critical development decisions by adding mechanistic insight that systemic measures alone cannot offer.

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How We Manufacture the RTube™

How We Manufacture the RTube™

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Because even trace contaminants can skew biomarker data, Respiratory Research, Inc. employs a proprietary cleaning process that removes both chemical residues and organic matter. Manufactured in an ISO 8 cleanroom, each RTube™ is sealed to guarantee pristine breath analysis—ensuring accurate breath biomarkers with every use.

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