Made in USA

Thank you all for visiting our booth at the American Thoracic Society International Conference 2015 in Denver last month.  It was great to see you and learn more about your specific research interests.  Three trends became evident from our conversations and a review of the abstracts presented:

  • The pace of exhaled biomarker research is accelerating
  • Measurement of Volatile Organic Compounds in exhaled breath is becoming central to the field
  • Potentially prognostic genetic markers of lung cancer in breath condensate are emerging

The 21 abstracts below were selected from the full list of ATS 2015 abstracts found at:

Hopefully we didn’t miss any relevant to the field of exhaled biomarker research, but if we did, please let us know and we’ll update this post.

As a side note, we specifically excluded eNO abstracts since this is becoming established clinically and is essentially a category in of itself.  Our focus continues to be on other emerging research.

Happy reading!


Functional and Inflammatory Abnormalities in Artificial Stone Exposed Workers

Noa OphirYifat AlcalayAmir Bar-ShaiLilach Israeli-shanyRafi Korenstein,Mordechai Kramer, , Elizabeth M. Fireman

A46. OCCUPATION, OBESITY, AND LUNG HEALTH, 2015: A1749, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A1749

Citation | PDF (18 KB)

Exhaled Carbon Monoxide: A Marker of Recent Household Air Pollution Exposure

Alison Lee, , Tiffany SanchezHasan ShahriarMahbubul EunusMatthew Perzanowski,Joseph Graziano

B46. HEALTH EFFECTS OF AIR POLLUTION AND NANOPARTICLES, 2015: A3234, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A3234

Citation | PDF (18 KB)

Relationship Between Airway Hyperresponsiveness to Hypoosmolar Stimulus and Inflammation in Asthma

Juliy M. PerelmanAnna G. PrikhodkoEvgenia Y. AfanasevaEvgeniy A. Borodin, ,Viktor P. Kolosov

A33. IMMUNE REGULATION OF INFLAMMATION AND AIRWAY HYPERRESPONSIVENESS, 2015: A1348, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A1348

Citation | PDF (19 KB)

Airway Metabolomics in Asthma

Deepa Rastogi, , Hardik B. ShahLizette DeLaRosaIrwin J. KurlandSimon D. Spivack

C38. BIOMARKERS OF ACUTE AND CHRONIC INFLAMMATION, 2015: A4307, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A4307

Citation | PDF (21 KB)

Airway Acidity in Critically Ill, Mechanically Ventilated Patients

Michael D. Davis, , Alison J. MontpetitWilliam AndersonR K. ElswickMichelle Jump,Megan A. ScottJohn F. Hunt

C38. BIOMARKERS OF ACUTE AND CHRONIC INFLAMMATION, 2015: A4339, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A4339

Citation | PDF (17 KB)

Exhaled microRNAs as Biomarkers of Lung Cancer Case Status

Simon D. SpivackMiao K. ShiJuan LinWeiguo Han,

B61. MANAGING LUNG CANCER SCREENING AND ITS DOWNSTREAM FINDINGS, 2015: A3583, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A3583

Citation | PDF (17 KB)

Ultrafine Particles (UFP) Content in Exhaled Breath Condensate (EBC) in Asthmatic Children Airways

Elizabeth M. FiremanShira BenorKeren Armoni DumaniYfat AlcalyGuy GutRuth SofermanShmuel Kivity,

D107. NOVEL ASTHMA EPIDEMIOLOGY AND MECHANISMS, 2015: A6269, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A6269

Citation | PDF (17 KB)

Detection of microRNAs Associated with Tumor Dissemination and Drug Resistance in Exhaled Breath in Lung Cancer

Wei Le, , W WongMueen GhaniRahul AhujaDaya Upadhyay

B57. GENE REGULATION: MIRNAS AND EPIGENETICS, 2015: A3482, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A3482

Citation | PDF (17 KB)

Short Term Biological Effects of e-Cigarette Vapor Exposures

Kelly Schweitzer, , Sarah LawChristophe PoirierXianyin LaiMu WangWilliam D. KranzClinton J. CarrollBruce D. RayJohn GoodpasterIrina Petrache

B28. BARRIER DYNAMICS IN THE PULMONARY CIRCULATION, 2015: A2654, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A2654

Citation | PDF (18 KB)

Comparison of Airway and Systemic Malondialdehyde Levels for Assessment of Oxidative Stress in Cystic Fibrosis

Balazs AntusOrsolya DrozdovszkyKrisztina KelemenImre Barta,

D45. CYSTIC FIBROSIS: FROM ION TRANSPORT TO OXIDANT METABOLISM, 2015: A6005, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A6005

Citation | PDF (17 KB)

Exhaled Breath Volatile Organic Compounds can Classify Asthma Patients with High and Low Sputum Eosinophils

Paul BrinkmanYuanyue WangSimone HashimotoHans WedaHugo H. Knobel,Teunis J. VinkNicholas J. RattrayPaolo MontuschiMarco SantonicoGiorgo PennazzaArnaldo D’AmicoPeter J. SterkStephen J. Fowler,

C38. BIOMARKERS OF ACUTE AND CHRONIC INFLAMMATION, 2015: A4310, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A4310

Citation | PDF (19 KB)

Comparison of Breath Volatile Organic Compounds Collected from Healthy Controls, Healthy Smokers, Smokers with COPD, and Ex-Smokers with COPD at Two German Centers for Lung Research (DZL)

Arne GaidaOlaf HolzSven Schuchardt, , Christoph NellUrsula BoasJens LangejürgenStefan ZimmermannAndreas R. KoczullaJens M. Hohlfeld

B31. INFLAMMATION AND COPD, 2015: A2727, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A2727

Citation | PDF (18 KB)

  Asthmatic Children that Are Uncontrolled Despite Inhaled Corticosteroids Have a Distinct Breathprint (The PACMAN2 Study)

Susanne VijverbergPaul BrinkmanJan RaaijmakersKors Van Der EntPeter J. Sterk, , Anke-Hilse Maitland-van Der ZeeLeo Koenderman

B21. TRANSLATIONAL ASTHMA RESEARCH, 2015: A2482, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A2482

Citation | PDF (18 KB)

Detection of Volatile Organic Compounds in the Exhaled Breath as Biomarkers for the Paratuberculosis in Goats by Ion Mobility Spectrometry

Gunther BecherHeike KoehlerWerner SchuelerRoman Purkhart, , Werner SteinhaeusserPetra Reinhold

A32. MICROBIAL INTERACTIONS AND HOST DEFENSE, 2015: A1340, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A1340

Citation | PDF (17 KB)

Analysis of Hydrogen Sulfide in Breath

Jack Dummer, , Malina StorerMaureen P. SwanneyChristopher FramptonMichael Epton

C38. BIOMARKERS OF ACUTE AND CHRONIC INFLAMMATION, 2015: A4336, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A4336

Citation | PDF (19 KB)

Volumetric Capnography as a Candidate Exhaled Biomarker for Patients with Rib Fractures

Alison Montpetit, , Michael DavisMegan ScottMichelle JumpLeroy ThackerEmily CochranChristi AdamsLois RowlandBeth BoeringJames WhelanV. R. Feeser

C38. BIOMARKERS OF ACUTE AND CHRONIC INFLAMMATION, 2015: A4338, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A4338

Citation | PDF (18 KB)

A Comparision on Non-Invasive Biomarkers of Airway Type-2 Inflammation in Asthma

Michael C. Peters, , Nirav R. BhaktaPrescott G. WoodruffJohn V. Fahy

B21. TRANSLATIONAL ASTHMA RESEARCH, 2015: A2483, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A2483

Citation | PDF (27 KB)

Exhaled microRNAs as Biomarkers of Lung Cancer Case Status

Simon D. SpivackMiao K. ShiJuan LinWeiguo Han,

B61. MANAGING LUNG CANCER SCREENING AND ITS DOWNSTREAM FINDINGS, 2015: A3583, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A3583

Citation | PDF (17 KB)

Exhaled Breath Analysis for Volatile Organic Compounds Reveals New Insights into the Pathogenesis of Irritable Bowel Syndrome

David GroveAmmar MatloobSophia Ali PatelVera OkwuRaed A. DweikNaim Alkhouri,

A33. IMMUNE REGULATION OF INFLAMMATION AND AIRWAY HYPERRESPONSIVENESS, 2015: A1371, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A1371

Citation | PDF (17 KB)

Integration of Electronic Nose Technology with Spirometry: Validation of a New Approach for Clinical Breath Analysis

Rianne De VriesPaul BrinkmanNiki FensErica DijkersSimon BootsmaFrans H.C. De JonghP.J. Sterk,

C32. CLINICAL ASTHMA II, 2015: A4184, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A4184

Citation | PDF (18 KB)

Volatile Organic Compounds (VOCs) in Exhaled Breath of Asthma Patients Differ Between Loss of Control and Stable Phase

Niki Fens, , Marianne A. Van De PolPaul BrinkmanMaria G. GerritsenLieuwe D.J. BosTamara DekkerBarbara S. SmidsChristof J. MajoorMarlous M.S. Sneeboer,René LutterPeter J. Sterk

C32. CLINICAL ASTHMA II, 2015: A4172, 10.1164/ajrccm-conference.2015.191.1_MeetingAbstracts.A4172

Citation | PDF (29 KB)

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