Breath Analysis Research Updates, Techniques, and How-To’s
Discover the latest in breath analysis and diagnostics on the Respiratory Research blog. Dive into in-depth articles on breath biomarkers, cutting-edge breath-based diagnostics, and effective exhaled breath condensate (EBC) collection techniques. Learn about the significance of RNA and microRNA isolation from EBC, the evolving standards for breath biomarkers, and insights on commercializing breath tests. Stay updated with practical tips and the latest research breakthroughs in the field of breath analysis.
How We Manufacture the RTube™
Because even trace contaminants can skew biomarker data, Respiratory Research, Inc. employs a proprietary cleaning process that removes both chemical residues and organic matter. Manufactured in an ISO 8 cleanroom, each RTube™ is sealed to guarantee pristine breath analysis—ensuring accurate breath biomarkers with every use.
Effectiveness of Exhaled Breath Condensate Collection Using RTube® and Cooling Sleeve Chilled in Household Freezer
Chilled in a household freezer, the RTube® reliably collects Exhaled Breath Condensate for breath analysis and breath biomarkers. This study shows yields remain near-constant across a wide temperature range, reinforcing RTube’s consistent performance in real-world clinical conditions.
Journal Article Summary – Measuring RNA in Breath Condensate
The RTube has successfully been used to isolate RNA, microRNA, and DNA from Exhaled Breath Condensate (EBC). While the collection process of EBC is similar for each target, the isolation steps differ. This Journal Article Summary, based on Dr. Guillermo Barreto’s EMBO Medicine study, highlights a non-invasive approach to nucleic acid isolation for early-stage lung cancer detection.
To Filter or Not To Filter
Examine the pros and cons of filtering exhaled breath samples. Learn how filtration affects sample purity, device performance, and data integrity for biomarker analysis.
An Evolving Standard for Exhaled Biomarkers in Lung Disease Meets Old-Fashioned Consistency
Delve into emerging guidelines that standardize exhaled biomarker collection and analysis. Understand how they shape the future of respiratory diagnostics and research.
FDA Commentary on Biomarker Qualification
Learn how recent FDA insights shape the qualification process for breath biomarkers. Discover the regulatory considerations that guide research and product approval.
The Drug-Device Breath Test
See how combining pharmaceuticals with breath analysis devices can revolutionize patient monitoring and therapy. Learn about challenges and innovations in this fast-growing field.
From Lab to Market: Commercializing Your Breath Test
Take your breath test from concept to commercialization with essential tips on product development, regulatory pathways, and funding strategies. Gain insights on turning lab breakthroughs into successful breath biomarkers and breath analysis products.
Tips and Methods: Collect EBC and Sample VOC’s Simultaneously
Master the art of collecting Exhaled Breath Condensate (EBC) alongside Volatile Organic Compounds (VOCs). Learn techniques that expand breath biomarker research by capturing both biochemical and volatile signatures in a single session.
Acid Breath Test May Help Identify Reopening of Collapsed Alveoli in ARDS
Discover how an acid breath test could reveal critical changes in alveolar function for ARDS patients. Gain insights into potential clinical impact and future applications.
A Simple Method for Comparing Cytokine Levels in Breath
Discover a streamlined approach to measure cytokine levels in Exhaled Breath Condensate (EBC), advancing breath biomarker research by simplifying the comparison of inflammatory markers across different breath analyses.
MicroRNA in Exhaled Breath May Help Predict Lung Cancer
Explore how microRNA in Exhaled Breath Condensate (EBC) could provide a non-invasive tool for early lung cancer detection, showcasing breath biomarker breakthroughs that may transform clinical diagnostics.
Selected Exhaled Biomarker Abstracts from ATS 2015
Discover selected exhaled biomarker abstracts from ATS 2015, spotlighting new findings to advance respiratory research and clinical practice.
What Makes a Breath Test Clinically Useful?
Uncover factors that elevate a breath test from concept to clinical relevance. Find out what clinicians, researchers, and regulatory bodies value in breath biomarker validation.
The Next Big Breath Test
Explore which cutting-edge breath biomarkers are poised to transform diagnostics. Gain insights into the latest research and potential clinical applications.